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EDAR Antibody (EDAR12), DyLight 650, Novus Biologicals™
SDP

Catalog No. NB016147 Shop All R&D Systems Products
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NB016147 0.1 mL
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Catalog No. NB016147 Supplier Novus Biologicals Supplier No. NBP281103C
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Description

Rabbit Monoclonal Antibody

EDAR Monoclonal specifically detects EDAR in Human, Mouse, Rat, Canine, Chicken samples. It is validated for Western Blot, ELISA, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen EDAR
Applications Western Blot, ELISA, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone EDAR12
Conjugate DyLight 650
Dilution Western Blot, ELISA, Immunocytochemistry/Immunofluorescence
Formulation 50mM Sodium Borate
Gene Alias Anhidrotic ectodysplasin receptor 1, DLED3, Ectodermal dysplasia receptor, ectodysplasin 1, anhidrotic receptor, ectodysplasin A receptor, Ectodysplasin-A receptor, ED1R, ED5, EDA1R, EDA3EDA-A1 receptor, EDA-A1R, Edar, FLJ94390, HRM1, mouse, homolog of, tumor necrosis factor receptor superfamily member EDAR
Gene Symbols EDAR
Host Species Rabbit
Immunogen EDAR12 was prepared by immunixzing female OVE1B mice (with the Edar gene deleted) subcutaneously with mouse EDAR-Fc and positive hybridoma clones were screened for binding mEDAR by ELISA.
Purification Method Protein A purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Apoptosis
Primary or Secondary Primary
Gene ID (Entrez) 10913
Test Specificity EDAR12 recognises and binds to CRD1 of the extracellular domain of mouse EDAR. EDAR3 cross-reacts with EDAR derived from human, dog, rat and chicken when EDAR is fused to the glycosylphosphatidylinositol anchor of TRAILR3. EDAR is the receptor for the TNF family ligand EDA1, which is a type II transmembrane protein possessing a collagen-like domain and a C-terminal TNF-homology domain. EDAR is important for the correct development of skin appendages including hair, teeth and eccrine sweat glands. LoF mutations in the Eda gene is known to cause XLHED (X-linked hypohidrotic ectodermal dysplasia), and results in abnormal development.
Target Species Human, Mouse, Rat, Canine, Chicken
Content And Storage Store at 4°C in the dark.
Form Purified
Isotype IgG κ
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