EGF R/ErbB1 Mouse, Clone: B1D8, Novus Biologicals™

Mouse Monoclonal Antibody has been used in 1 publication

Supplier:  Novus Biologicals NBP2328430.02MG

Catalog No. NBP232843F

Description

EGFR Monoclonal specifically detects EGFR in Human, Mouse (Negative), Rat (Negative) samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunoaffinity Purification.

Specifications

• Antigen: EGFR
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
• Host Species: Mouse
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: This antibody reacts with the extracellular domain of EGFR and blocks the EGF/TGF??induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin.
• Content And Storage: Store at 4C.
• Isotype: IgG2a κ

• Applications: Flow Cytometry, Immunoprecipitation
• Clone: B1D8
• Dilution: Flow Cytometry 0.5-1ug/million cells, Immunoprecipitation 0.5-1ug/500ug protein lysate
• Gene Accession No.: P00533
• Gene Symbols: EGFR
• Immunogen: Microsomes from A431 cells
• Quantity: 0.02 mg
• Research Discipline: Cancer, Cell Biology, Cell Cycle and Replication, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
• Gene ID (Entrez): 1956
• Target Species: Human, Mouse (Negative), Rat (Negative)
• Form: Purified