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EGFR Antibody (31G7), PE/Cy7, Novus Biologicals™
SDP

Catalog No. N247740PEC7 Shop All R&D Systems Products
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N247740PEC7 0.1 mL
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Catalog No. N247740PEC7 Supplier Novus Biologicals Supplier No. NBP247740PECY7
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Mouse Monoclonal Antibody

EGFR Monoclonal specifically detects EGFR in Human samples. It is validated for Flow Cytometry.

Specifications

Antigen EGFR
Applications Flow Cytometry
Classification Monoclonal
Clone 31G7
Conjugate PE-Cyanine7
Dilution Flow Cytometry
Formulation PBS with 0.05% Sodium Azide
Gene Alias avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Gene Symbols EGFR
Host Species Mouse
Immunogen Human EGFR purified from A431 cells
Purification Method Protein A or G purified
Quantity 0.1 mL
Research Discipline Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
Primary or Secondary Primary
Gene ID (Entrez) 1956.0
Test Specificity This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Target Species Human
Content And Storage Store at 4°C in the dark. Do not freeze.
Isotype IgG2a κ
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