EGFR Antibody (GFR450), PE/Cy5.5, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP233068PECY55

Catalog No. N233068PEC5

Description

EGFR Monoclonal specifically detects EGFR in Human, Mouse (Negative) samples. It is validated for Flow Cytometry.

Specifications

• Antigen: EGFR
• Classification: Monoclonal
• Conjugate: PE-Cyanine5.5
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: EGFR
• Immunogen: Recombinant extracellular domain of human EGFR protein (Uniprot: P00533)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: This monoclonal antibody recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
• Content And Storage: Store at 4°C in the dark. Do not freeze.

• Applications: Flow Cytometry
• Clone: GFR450
• Dilution: Flow Cytometry
• Gene Alias: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
• Gene ID (Entrez): 1956.0
• Target Species: Human, Mouse (Negative)
• Isotype: IgG2a κ