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Invitrogen™ eIF2b alpha Polyclonal Antibody
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Catalog No. PIPA5121151
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100 μL
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PIPA5121151 100 μL
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Catalog No. PIPA5121151 Supplier Invitrogen™ Supplier No. PA5121151
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Description

Rabbit Polyclonal Antibody

Positive test controls include: SH-SY5Y, MCF7, SKOV3, NCI-H460, Mouse liver, Mouse brain. Immunogen sequence: MDDKELIEYF KSQMKEDPDM ASAVAAIRTL LEFLKRDKGE TIQGLRANLT SAIETLCGVD SSVAVSSGGE LFLRFISLAS LEYSDYSKCK KIMIERGELF LRRISLSRNK IADLCHTFIK DGATILTHAY SRVVLRVLEA AVAAKKRFSV YVTESQPDLS GKKMAKALCH LNVPVTVVLD AAVGYIMEKA DLVIVGAEGV VENGGIINKI GTNQMAVCAK AQNKPFYVVA ESFKFVRLFP LNQQDVPDKF KYKADTLKVA QTGQDLKEEH PWVDYTAPSL ITLLFTDLGV LTPSAVSDEL IKLYL.

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
TRUSTED_SUSTAINABILITY

Specifications

Antigen eIF2b alpha
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.89 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene EIF2B1
Gene Accession No. Q14232, Q99LC8
Gene Alias 26kDa; D5Ertd406e; eIF-2a; EIF2B; eIF-2B GDP-GTP exchange factor subunit alpha; Eif2b1; EIF2BA; eIF-2Balpha; eukaryotic translation initiation factor 2B subunit alpha; eukaryotic translation initiation factor 2B, subunit 1 (alpha); eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kDa); eukaryotic translation initiation factor 2B, subunit 1 alpha; eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; GTP-exchange protein; translation initiation factor eIF-2B subunit alpha
Gene Symbols EIF2B1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-305 of human EIF2B1 (NP_001405.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1967, 209354
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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