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EIF4E Monoclonal Antibody (OTI6C3), TrueMAB™, OriGene
SDP

Catalog No. 501673896
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50-167-3896 100 μL
50-254-1239 30 μL
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Catalog No. 50-167-3896 Supplier OriGene Supplier No. TA502896
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Description

Mouse Monoclonal Antibody

All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.

Specifications

Antigen EIF4E
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI6C3
Concentration 0.52 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene EIF4E
Gene Accession No. P06730
Gene Alias AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E
Gene Symbols EIF4E
Host Species Mouse
Immunogen Full length human recombit protein of human EIF4E produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1977
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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