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eIF4E Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Catalog No. 501559394
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Quantity:
100 μL
Catalog No. Quantity
50-155-9394 100 μL
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Catalog No. 50-155-9394

Supplier: Bethyl Laboratories, Inc A301154A

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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, X. laevis, Bovine and Rabbit

All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G. (Rychlik et al., 1987 [PubMed 3469651]).

Specifications

Antigen eIF4E
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene EIF4E
Gene Accession No. P06730, P63073
Gene Alias Eukaryotic translation initiation factor 4E; eIF4E; eIF-4E; mRNA cap-binding protein; eIF-4F 25 kDa subunit; EIF4EL1; EIF4F
Gene Symbols EIF4E
Host Species Rabbit
Immunogen Between 167 and 217
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13684, 1977
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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