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Invitrogen™ eIF6 Polyclonal Antibody
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Catalog No. PIPA579196
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100 μg
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PIPA579196 100 μg
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Catalog No. PIPA579196 Supplier Invitrogen™ Supplier No. PA579196
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Liver Tissue, Rat Kidney Tissue, COLO320 Cell, SW620 Cell, HELA Cell, 293T Cell, HEPA Cell. IHC: Human Intestinal Cancer Tissue IHC-F: Human Placenta Tissue.

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding two different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen eIF6
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene Eif6
Gene Accession No. O55135, P56537, Q3KRD8
Gene Alias 1110004P11; AA408895; b(2)gcn; B(2)GCN homolog; B4 integrin interactor; CAB; EIF3A; Eif6; eIF-6; eIF-6 {ECO:0000255; eukaryotic translation initiation factor 3A; eukaryotic translation initiation factor 6; eukaryotic translation initiation factor 6 {ECO:0000255; HAMAP-Rule:MF_03132}; imc-415; integrin beta 4 binding protein; Itgb4bp; OK/SW-cl.27; p27 beta-4 integrin-binding protein; p27(BBP); p27BBP
Gene Symbols Eif6
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence in the middle region of human EIF6 (82-96aa QHIRNSLPDTVQIRR).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16418, 305506, 3692
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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