Elastin Antibody (ELN/1981), DyLight 755, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP275770IR

Catalog No. NB009067

Description

Elastin Monoclonal specifically detects Elastin in Human samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Elastin
• Classification: Monoclonal
• Conjugate: DyLight 755
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: ELN
• Immunogen: Recombinant full-length human Elastin protein (Uniprot: P15502)
• Quantity: 0.1 mL
• Research Discipline: Extracellular Matrix
• Test Specificity: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
• Content And Storage: Store at 4°C in the dark.

• Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)
• Clone: ELN/1981
• Dilution: ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin
• Gene Alias: elastin, FLJ38671, FLJ43523, SVAS, tropoelastin, WBS, WS
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Isotype: IgG1 κ