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Endoglin/CD105 Antibody (MJ7/18), DyLight 594, Novus Biologicals™
SDP

Catalog No. NB015704 Shop All R&D Systems Products
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NB015704 0.1 mL
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Catalog No. NB015704 Supplier Novus Biologicals Supplier No. NBP281085DL594
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Description

Rabbit Monoclonal Antibody

Endoglin/CD105 Monoclonal specifically detects Endoglin/CD105 in Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen Endoglin/CD105
Applications Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone MJ7/18
Conjugate DyLight 594
Dilution Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence
Formulation 50mM Sodium Borate
Gene Alias CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, HHT1FLJ41744, ORW, ORW1
Gene Symbols ENG
Host Species Rabbit
Immunogen MJ7/18 was prepared by immunizing rats with inflamed mouse skin tissue. The antibody was selected immunohistologically for reactivity with endothelial cells.
Purification Method Protein A purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer, Cell Biology, Cellular Markers, Endothelial Cell Markers, Extracellular Matrix, Hypoxia, Immunology, Mesenchymal Stem Cell Markers, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 2022
Test Specificity MJ7/18 binds specifically to mouse Endoglin/CD105. Endoglin/CD105 is a homodimer expressed by vascular endothelial cells. Endoglin/CD105 functions in adhesion and embryonic angiogenesis. Endoglin/CD105 is a major homodimeric glycoprotein of vascular endothelium involved in cell ahesion through integrin/RGD binding and the regulation of angiogenesis. Also acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Endoglin/CD105 is also required for GDF2/BMP9 signaling through SMAD1 in endothelial cells.
Target Species Mouse
Content And Storage Store at 4°C in the dark.
Form Purified
Isotype IgG κ
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