Enolase 2/Neuron-specific Enolase Antibody (ENO2/1375), Allophycocyanin/Cy7, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP254452APCCY7

Catalog No. N254452APC7

Description

Enolase 2/Neuron-specific Enolase Monoclonal specifically detects Enolase 2/Neuron-specific Enolase in Human, Mouse, Rat samples. It is validated for Flow Cytometry, Flow (Intracellular).

Specifications

• Antigen: Enolase 2/Neuron-specific Enolase
• Classification: Monoclonal
• Conjugate: APC-Cyanine7
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: ENO2
• Immunogen: A synthetic peptide of human Enolase 2/Neuron-specific Enolase (around aa416-433) (exact sequence is proprietary) (Uniprot: P09104)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament.
• Content And Storage: Store at 4°C in the dark. Do not freeze.

• Applications: Flow Cytometry
• Clone: ENO2/1375
• Dilution: Flow Cytometry, Flow (Intracellular)
• Gene Alias: 2-phospho-D-glycerate hydrolyase, 2-phospho-D-glycerate hydro-lyase, EC 4.2.1.11, Enolase 2, enolase 2 (gamma, neuronal), gamma-enolase, Neural enolase, neuron specific gamma enolase, neurone-specific enolase, Neuron-specific enolase, NSE
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Cancer, Cellular Markers, Neuronal Cell Markers, Neuroscience
• Gene ID (Entrez): 2026.0
• Target Species: Human, Mouse, Rat
• Isotype: IgG2b κ