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  5. Tocris Bioscience™ Entacapone

Tocris Bioscience™ Entacapone
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Catalog No. p-4816692
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent COMT inhibitor; blocks α-synuclein aggregation

Potent catechol O-methyltransferase (COMT) inhibitor (IC50 values are 14.3, 20.1 and 73.3 nM for rat liver soluble COMT, total COMT and membrane-bound COMT respectively). Increases bioavailability of levodopa when given as an adjunct therapy for Parkinson's disease. Inhibits α-synuclein aggregation in an in vitro assay; blocks α-synuclein-induced cell death in PC-12 cells.

Chemical Identifiers

CAS 130929-57-6
Molecular Formula C14H15N3O5

Specifications

Quantity 10 mg
Formula Weight 305.29
Purity >99%
Molecular Weight (g/mol) 305.29
Chemical Name or Material Entacapone

Safety and Handling

Recommended Storage Store at Room Temperature
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