EPAS1 Monoclonal Antibody (OTI2A6), TrueMAB™, OriGene

Catalog No.	Quantity
50-167-8961	100 μL

Catalog No. 50-167-8961 Supplier OriGene Supplier No. TA801749

Description

Mouse Monoclonal Antibody

HIF-2 alpha (Epas1) is a transcription factor involved in the induction of genes regulated by oxygen. HIF-2 alpha contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. It also regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of the lungs. Mutations in this gene are associated with erythrocytosis familial type 4.

Specifications

• Antigen: EPAS1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI2A6
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: EPAS1
• Gene Accession No.: Q99814
• Gene Alias: ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73
• Gene Symbols: EPAS1
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 584-870 of human EPAS1 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2034
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1