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EpCAM/TROP1 Antibody (EGP40/1555R), PE/Cy5.5 - (ECD), Novus Biologicals™
SDP

Catalog No. N254424PEC5 Shop All R&D Systems Products
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Catalog No. N254424PEC5 Supplier Novus Biologicals Supplier No. NBP254424PECY55
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Description

Rabbit Monoclonal Antibody

EpCAM/TROP1 Monoclonal specifically detects EpCAM/TROP1 in Human, Mouse (Negative), Rat (Negative) samples. It is validated for Flow Cytometry.

Specifications

Antigen EpCAM/TROP1
Applications Flow Cytometry
Classification Monoclonal
Clone EGP40/1555R
Conjugate PE-Cyanine5.5
Dilution Flow Cytometry
Formulation PBS with 0.05% Sodium Azide
Gene Alias 17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A
Gene Symbols EPCAM
Host Species Rabbit
Immunogen Recombinant full-length human EpCAM/TROP1 protein (Uniprot: P16422 )
Purification Method Protein A purified
Quantity 0.1 mL
Research Discipline Cancer, Cancer Stem Cells, Tumor Biomarkers
Primary or Secondary Primary
Gene ID (Entrez) 4072.0
Test Specificity Recognizes a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (EpCAM). EpCAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
Target Species Human, Mouse (Negative), Rat (Negative)
Content And Storage Store at 4°C in the dark. Do not freeze.
Isotype IgG
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