EpCAM/TROP1 Antibody (PAN-EpCAM (Cocktail)), PE/Atto594, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP247878PEATT594

Catalog No. N247878P594

Description

EpCAM/TROP1 Monoclonal specifically detects EpCAM/TROP1 in Human samples. It is validated for Flow Cytometry.

Specifications

• Antigen: EpCAM/TROP1
• Classification: Monoclonal
• Conjugate: PE/ATTO 594
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: EPCAM
• Immunogen: Recombinant human EpCAM/TROP1 protein (full-length and fragments) (Uniprot: P16422 )
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: It is a cocktail of four highly specific monoclonal antibodies that recognize extracellular as well as intracellular domains of the epithelial cellular adhesion molecule (EpCAM). It is a 40-43kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or EpCAM. EpCAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
• Content And Storage: Store at 4°C in the dark. Do not freeze.

• Applications: Flow Cytometry
• Clone: PAN-EpCAM (Cocktail)
• Dilution: Flow Cytometry
• Gene Alias: 17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2EGP34, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Cancer, Cancer Stem Cells, Tumor Biomarkers
• Gene ID (Entrez): 4072.0
• Target Species: Human
• Isotype: IgG1 κ