EphA2, Human anti-Human, Clone: 1C1, Novus Biologicals™

Human Monoclonal Antibody

Supplier:  Novus Biologicals NBP2810690.2MG

Catalog No. NB015314

Description

EphA2 Monoclonal specifically detects EphA2 in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Block/Neutralize.

Specifications

• Antigen: EphA2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Block/Neutralize
• Gene Alias: ARCC2, EC 2.7.10, EC 2.7.10.1, ECKepithelial cell receptor protein tyrosine kinase, EPH receptor A2, EphA2, ephrin type-A receptor 2, Epithelial cell kinase, soluble EPHA2 variant 1, Tyrosine-protein kinase receptor ECK
• Host Species: Human
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: 1C1 binds specifically to the amino-termianal LBD (ligand-binding domain) region of the EphA2 ectodomain (IgG1 KD ∽0.8 nM; Fab KD ∽140 nM) and not to other related human Eph receptors such as EphA1, EphA2, and EphA4, or any EphB receptor family members.
• Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Isotype: IgG1 κ

• Applications: Western Blot, Flow Cytometry, ELISA, Immunofluorescence, Blocking Assay
• Clone: 1C1
• Conjugate: Unconjugated
• Formulation: PBS
• Gene Symbols: EPHA2
• Immunogen: 1C1 was isolated after screening of a non-immunized human Fab phage library. Selection was based on the ability to bind soluble human recombinant EphA2 (residues 183-510). The Fab was subsequently converted to full length human IgG1.
• Quantity: 0.2 mg
• Research Discipline: Cancer, Protein Kinase
• Gene ID (Entrez): 1969
• Target Species: Human
• Form: Purified