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Thermo Scientific™ Lab Vision™ Epidermal Growth Factor Receptor/EGFR Ab-2, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-2, Mouse Monoclonal Antibody.

$220.00 - $984.50

Specifications

Antigen Epidermal Growth Factor Receptor/EGFR Ab-2
Clone 225
Applications Immunoprecipitation
Classification Monoclonal
Conjugate Unconjugated
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Products 5
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
MS269P
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Thermo Scientific™
MS269P
200μg/mL 1mL Each for $853.00
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MS269P0
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Thermo Scientific™
MS269P0
200μg/mL 100μL Each for $220.00
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MS269P1
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Thermo Scientific™
MS269P1
200μg/mL 500μL Each for $454.00
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MS269P1ABX
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Thermo Scientific™
MS269P1ABX
1mg/mL 100μL Each for $624.00
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MS269PABX
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Thermo Scientific™
MS269PABX
1mg/mL 200μL Each for $984.50
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Description

Description

Ensure accurate, reproducible results in immunoprecipitation experiments with Thermo Scientific™ Epidermal Growth Factor Receptor/EGFR Ab-2, Mouse Monoclonal Antibody.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: 225

Isotype: IgG1

Species Reactivity: Human, Chimpanzee and Monkey. Does not react with mouse and rat. Others not known.

Epitope: Extracellular domain

Immunogen: Purified EGFR from A431 cells

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells

Cellular Localization: Membrane

Recommended for:

  • Immunoprecipitation (Native only)
  • Blocks EGF/TGFα-Induced Activation of EGFR
  • Arrests Tumor Growth in vivo
  • Inhibits Binding of Ab-1 (clone 528) to EGFR

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Epidermal Growth Factor Receptor/EGFR Ab-2
Immunoprecipitation
Unconjugated
Murine
EGFR Family
Purified EGFR from A431 cells
225
Monoclonal
Concentrated
RUO
Primary
IgG1
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