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Epidermal Growth Factor Receptor/EGFR Ab-2 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results in immunoprecipitation experiments with Epredia™ Epidermal Growth Factor Receptor/EGFR Ab-2, Mouse Monoclonal Antibody.
$298.00 - $593.00
Specifications
| Antigen | Epidermal Growth Factor Receptor/EGFR Ab-2 |
|---|---|
| Clone | 225 |
| Applications | Immunoprecipitation |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Concentration | Quantity | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Concentration | Quantity | Price | Quantity & Availability | ||||
|
MS269P0
|
Epredia
MS269P0 |
200μg/mL | 100 μL |
Each for $298.00
|
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MS269P1
|
Epredia
MS269P1 |
200μg/mL | 500 μL |
Each for $593.00
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MS269P
|
Epredia
MS269P |
200μg/mL | 1 mL | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | ||||
|
MS269P1ABX
|
Epredia
MS269P1ABX |
1mg/mL | 100 μL | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | ||||
|
MS269PABX
|
Epredia
MS269PABX |
1mg/mL | 200 μL | Item Discontinued This item has been discontinued by the supplier. Please Sign In to view product availability in your area. | N/A | ||||
Description
EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Host Species: Mouse
Clone: 225
Isotype: IgG1
Species Reactivity: Human, Chimpanzee and Monkey. Does not react with mouse and rat. Others not known.
Epitope: Extracellular domain
Immunogen: Purified EGFR from A431 cells
Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)
Positive Control: A431 cells
Cellular Localization: Membrane
Recommended for:
- Immunoprecipitation (Native only)
- Blocks EGF/TGFα-Induced Activation of EGFR
- Arrests Tumor Growth in vivo
- Inhibits Binding of Ab-1 (clone 528) to EGFR
Note:
USA: RUO; Int'l: RUO
Specifications
| Epidermal Growth Factor Receptor/EGFR Ab-2 | |
| Immunoprecipitation | |
| Unconjugated | |
| Mouse | |
| EGFR Family | |
| Purified EGFR from A431 cells | |
| Primary |
| 225 | |
| Monoclonal | |
| Concentrated | |
| RUO | |
| Human, Non-human Primate | |
| IgG1 |
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