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  6. Epidermal Growth Factor Receptor/EGFR Ab-5 Mouse Monoclonal Antibody, Epredia™

Epidermal Growth Factor Receptor/EGFR Ab-5 Mouse Monoclonal Antibody, Epredia™

Catalog No. ms316p1abx Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Concentration:
1mg/mL
200μg/mL
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Catalog No. Quantity Concentration
MS316P1ABX 100 μL 1mg/mL
MS316P1 500 μL 200μg/mL
MS316PABX 200 μL 1mg/mL
MS316P0 100 μL 200μg/mL
MS316P 1 mL 200μg/mL
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Description

Obtain accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence, immunoprecipitation and flow cytometry experiments.

EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Host Species: Mouse

Clone: H11

Isotype: IgG1/κ

Species Reactivity: Human. Does not react with mouse and rat. Others not known.

Epitope: Extracellular domain

Immunogen: HC2 20 d2 cells

Molecular Weight: 170 kDa (wild type) and 145 kDa (vIII variant)

Positive Control: A431 cells, Placenta or Squamous cell CA

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native only)
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Antigen Epidermal Growth Factor Receptor/EGFR Ab-5
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone H11
Concentration 1mg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen HC2 20 d2 cells
Quantity 100 μL
Regulatory Status RUO
Research Discipline EGFR Family
Primary or Secondary Primary
Target Species Human
Form Concentrated
Isotype IgG1 κ
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