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Invitrogen™ Epstein Barr Virus LMP2 Polyclonal Antibody
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Catalog No. PIPA5117557
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100 μg
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PIPA5117557 100 μg
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Catalog No. PIPA5117557 Supplier Invitrogen™ Supplier No. PA5117557
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Description

Rabbit Polyclonal Antibody

This antibody has been tested in direct-ELISA.

Epstein Barr virus (EBV) is a member of the herpesvirus family and one of the most common human viruses. Most people become infected with EBV during their lives. Primary infections usually results in infectious mononucleosis (glandular fever) but the virus can also lay dormant in B lymphocytes and when reactivated become associated with more serious disease such as Burkitt's lymphoma, nasopharyngeal carcinoma and Hodgkin's disease. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Epstein Barr Virus LMP2
Applications ELISA
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Host Species Rabbit
Immunogen Recombinant Epstein-Barr virus Latent membrane protein 2 protein (1-147aa).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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