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EPX Antibody (AHE-1), Novus Biologicals™
SDP

Catalog No. NBP232964F Shop All R&D Systems Products
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NBP232964F 0.02 mg
NBP232964A 0.1 mg
NBP232964B 0.2 mg
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Catalog No. NBP232964F Supplier Novus Biologicals Supplier No. NBP2329640.02MG
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Mouse Monoclonal Antibody

EPX Monoclonal specifically detects EPX in Human samples. It is validated for ELISA.

Specifications

Antigen EPX
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone AHE-1
Conjugate Unconjugated
Dilution Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P11678
Gene Alias EC 1.11.1.7, eosinophil peroxidase, EPOEPER, EPPEC 1.11.1, EPX-PEN
Gene Symbols EPX
Host Species Mouse
Immunogen Human eosinophils from a patient with hypereosinophilic syndrome
Purification Method Protein A purified
Quantity 0.02 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8288
Test Specificity Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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