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ER alpha/NR3A1 Mouse, Clone: AER314, Novus Biologicals™
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Catalog No. NBP248012B Shop All R&D Systems Products
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0.2 mg
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NBP248012B 0.2 mg
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Catalog No. NBP248012B Supplier Novus Biologicals Supplier No. NBP2480120.2MG

Description

Mouse Monoclonal Antibody

ER alpha/NR3A1 Monoclonal antibody specifically detects Antigen in Bovine, Human, Mouse, Rabbit, Rat samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

Antigen ER alpha/NR3A1
Applications Flow Cytometry, Immunofluorescence, CyTOF
Classification Monoclonal
Clone AER314
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 1 - 2 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias ER, ER alpha, Era, ER-alpha, ESRESRA, Estradiol receptor, estrogen receptor, estrogen receptor 1, estrogen receptor alpha, estrogen receptor alpha delta 3*4,56,7*/819-2 isoform, estrogen receptor alpha delta 4 +49 isoform, estrogen receptor alpha delta 4*5,6,7*/654 isoform, NR3A1DKFZp686N23123, Nuclear receptor subfamily 3 group A member 1
Gene Symbols ESR1
Host Species Mouse
Immunogen ER purified from cow uterus
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Angiogenesis, Breast Cancer, Cancer, Cell Biology, Cell Cycle and Replication, Dendritic Cell Markers, GPCR, Neuroscience, Signal Transduction, Transcription Factors and Regulators
Primary or Secondary Primary
Gene ID (Entrez) 2099
Test Specificity This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this MAb is mapped between aa120-170. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Target Species Human, Mouse, Rat, Bovine, Rabbit
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1
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