ER-HR3 Antibody (ER-HR3) - BSA Free, Novus Biologicals™

Rat Monoclonal Antibody

Supplier:  Novus Biologicals NB100649310.025MG

Catalog No. NB017667

Description

ER-HR3 Monoclonal specifically detects ER-HR3 in Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen.

Specifications

• Antigen: ER-HR3
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: Flow Cytometry 1:10-1:50, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
• Gene Alias: Hematopoiesis related macrophage
• Immunogen: Adherent F1 (CBAxBL) bone marrow stormal cells.
• Quantity: 0.025 mg
• Primary or Secondary: Primary
• Target Species: Mouse
• Form: Purified

• Applications: Immunohistochemistry (Frozen), Immunofluorescence, Immunocytochemistry, Immunohistochemistry, Flow Cytometry
• Clone: ER-HR3
• Conjugate: Unconjugated
• Formulation: PBS (pH 7.4) with 0.09% Sodium Azide
• Host Species: Rat
• Purification Method: Protein G purified
• Regulatory Status: RUO
• Test Specificity: NB100-64931 recognizes the murine antigen ER-HR3. ER-HR3 is a cell surface antigen which is expressed by Langerhans cells in epithelium, a subset of mature macrophages and dendritic cells that are located predominantly in haematopoietic and lymphoid organs. Initial studies of ER-HR3 demonstrated expression on peripheral blood monocytes but recent studies suggest that expression is actually very low. During foetal development, ER-HR3 positive cells are localised to haemapoietic islands and are often associated with erythroid progenitor cells. The functions of the ER-HR3 antigen have not been established but reports suggest that the antigen may be involved in adult erythropoiesis and in the regulation of the immune response. Clone ER-HR3 does not inhibit T cell proliferation in antigen-specific T-cell proliferation studies. Clone ER-HR3 recognizes two proteins of approximately 69kD and 55kD under non-reducing conditions.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG2c

For Research Use Only