ER-HR3 Antibody (ER-HR3), DyLight 650

Rat Monoclonal Antibody

Supplier:  Novus Biologicals NB10064931C

Catalog No. NB10064931C

Description

ER-HR3 Monoclonal specifically detects ER-HR3 in Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen.

Specifications

• Antigen: ER-HR3
• Classification: Monoclonal
• Conjugate: DyLight 650
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Host Species: Rat
• Quantity: 0.125 mL
• Test Specificity: NB100-64931 recognizes the murine antigen ER-HR3. ER-HR3 is a cell surface antigen which is expressed by Langerhans cells in epithelium, a subset of mature macrophages and dendritic cells that are located predominantly in haematopoietic and lymphoid organs. Initial studies of ER-HR3 demonstrated expression on peripheral blood monocytes but recent studies suggest that expression is actually very low. During foetal development, ER-HR3 positive cells are localised to haemapoietic islands and are often associated with erythroid progenitor cells. The functions of the ER-HR3 antigen have not been established but reports suggest that the antigen may be involved in adult erythropoiesis and in the regulation of the immune response. Clone ER-HR3 does not inhibit T cell proliferation in antigen-specific T-cell proliferation studies. Clone ER-HR3 recognizes two proteins of approximately 69kD and 55kD under non-reducing conditions.
• Content And Storage: Store at 4°C in the dark.

• Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
• Clone: ER-HR3
• Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
• Gene Alias: Hematopoiesis related macrophage
• Immunogen: Adherent F1 (CBAxBL) bone marrow stormal cells.
• Primary or Secondary: Primary
• Target Species: Mouse
• Isotype: IgG2c