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ErbB2/Her2 Antibody (HRB2/258), DyLight 350, Novus Biologicals™
SDP

Catalog No. NBP234641UV Shop All R&D Systems Products
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Catalog No. NBP234641UV Supplier Novus Biologicals Supplier No. NBP234641UV
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Mouse Monoclonal Antibody

ErbB2/Her2 Monoclonal specifically detects ErbB2/Her2 in Human, Mouse, Rat samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen ErbB2/Her2
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone HRB2/258
Conjugate DyLight 350
Dilution Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)
Gene Symbols ERBB2
Host Species Mouse
Immunogen Recombinant extracellular domain of human ErbB2/Her2 protein (Uniprot: IDP04626)
Molecular Weight of Antigen 185 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Breast Cancer, Cancer, Cellular Markers, Core ESC Like Genes, Protein Kinase, Stem Cell Markers, Tumor Suppressors
Primary or Secondary Primary
Gene ID (Entrez) 2064
Test Specificity Recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This monoclonal antibody is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. C-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Target Species Human, Rat
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG2a κ
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