Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
ERLIN2 Monoclonal Antibody (C2), Invitrogen™
Mouse Monoclonal Antibody
$243.00 - $552.50
Specifications
| Antigen | ERLIN2 |
|---|---|
| Clone | C2 |
| Concentration | 1 mg/mL |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
PIMA543835
|
Invitrogen™
MA543835 |
20 μL |
Each for $243.00
|
|
|||||
|
PIMA543834
|
Invitrogen™
MA543834 |
100 μL |
Each for $552.50
|
|
|||||
Description
ERLIN2, also named as C8orf2 and SPFH2, is a component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1, 4, 5-trisphosphate receptors (IP3Rs) such as ITPR1. It promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. ERLIN2 is involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. The MW of ERLIN1/ERLIN2 complex is about 70 kDa.Specifications
| ERLIN2 | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 | |
| BC036333; C87251; C8orf2; EMBL:AAI68668.1, ECO:0000312; EMBL:AAI68668.1}; endoplasmic reticulum lipid raft-associated protein 2; endoplasmic reticulum lipid raft-associated protein 2 {ECO:0000250; ER lipid raft associated 2; Erlin2; erlin-2; erlin-2 {ECO:0000250; erlin2 {ECO:0000312; HGNC:1356; MGC87072; NET32; RGD:1309010}; RGD1309010; SPFH domain family, member 2; SPFH domain-containing protein 2; SPFH domain-containing protein 2 {ECO:0000250; Spfh2; SPG18; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2 {ECO:0000250; UniProtKB:Q8BFZ9, ECO:0000312; UniProtKB:Q8BFZ9}; UNQ2441; UNQ2441/PRO5003/PRO9924 | |
| ERLIN2 | |
| IgG2a λ | |
| Protein A/G | |
| Antibody |
| C2 | |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Mouse | |
| Human | |
| O94905 | |
| 11160 | |
| Pro47-Asn339 (Accession O94905), with N-terminal His Tag. | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| ERLIN2 |
Spot an opportunity for improvement?Share a Content Correction
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title