ESRP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-173-4001	Proteintech Group Inc 231171AP150UL	150 μL

Description

RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5′ UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing program induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.

Specifications

• Antigen: ESRP2
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q8K0G8, Q9H6T0
• Gene ID (Entrez): 77411, 80004
• Immunogen: ESRP2 Fusion Protein Ag19436
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ESRP2

• Concentration: 0.21 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: ESRP2, RBM35B, RNA binding motif protein 35B, RNA binding protein 35B
• Gene Symbols: Esrp2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody