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Invitrogen™ EXO5 Polyclonal Antibody
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Catalog No. PIPA5110957
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100 μL
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PIPA5110957 100 μL
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Catalog No. PIPA5110957 Supplier Invitrogen™ Supplier No. PA5110957
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ELPGFLAPEK AAVLDTGASI HLARELELHD LVTVPVTTKE DAWAIKFLNI LLLIPTLQSE GHIREFPVFG EVEGVLLVGV IDELHYTAKG Highest antigen sequence indentity to the following orthologs: Rat - 86%, Mouse - 84%.

Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends. Acts as a sliding exonuclease that loads at ssDNA ends and then slides along the ssDNA prior to cutting; however the sliding and the 3'-5' exonuclease activities are abolished upon binding to the replication protein A (RPA) complex that enforces 5'- directionality activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen EXO5
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Exo5
Gene Accession No. Q9H790
Gene Alias 3110037I16Rik; AV297100; C1orf176; defects in morphology 1 homolog; defects in morphology protein 1 homolog; Defects in morphology protein 1-like; Dem1; Exo V; EXO5; exonuclease 5; exonuclease V; hExo5; mExo5; probable exonuclease V
Gene Symbols Exo5
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human EXO5. Recombinant protein control fragment (Product #RP-94441).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64789
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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