EZH2 Monoclonal Antibody (AC22), Active Motif™

Mouse Monoclonal Antibody

Supplier:  Active Motif 39876

Catalog No. 50-199-2920

Description

EZH2 (Histone-lysine N-methyltransferase) is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Mutations affecting EZH2 can cause Weaver syndrome (WVS).

Specifications

• Antigen: EZH2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
• Gene Accession No.: Q15910, Q61188
• Gene Symbols: EZH2
• Immunogen: This EZH2 antibody was raised against a recombinant protein corresponding to amino acids 353-451 of human EZH2.
• Quantity: 10 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: ChIP Assay
• Clone: AC22
• Conjugate: Unconjugated
• Gene: EZH2
• Gene Alias: an; enhancer of zeste 2 polycomb repressive complex 2 subunit; Enhancer of zeste homolog 2; enhancer of zeste homolog 2 (Drosophila); ENX 1; ENX1; ENX-1; Enx1h; EZH 2; EZH1; Ezh2; EZH-2; EZH2b; Histone-lysine N-methyltransferase EZH2; KMT6; KMT6A; Lysine N-methyltransferase 6; mKIAA4065; OTTHUMP00000213774; OTTHUMP00000213778; OTTHUMP00000213779; OTTHUMP00000213780; WVS; WVS2
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 14056, 2146
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid