Factor XIIIa Mouse anti-Human, Clone: F13A1/1448, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP25960420UG

Catalog No. NBP25960420

Description

Factor XIIIa Monoclonal specifically detects Factor XIIIa in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array.

Specifications

• Antigen: Factor XIIIa
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Dilution: Western Blot 0.5-1.0 ug/ml, Flow Cytometry 0.5-1 ug/million cells, ELISA 2-4 ug/ml, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml, SDS-Page, Protein Array 1:100-1:2000
• Gene Alias: bA525O21.1 (coagulation factor XIII, A1 polypeptide), coagulation factor XIII A chain, coagulation factor XIII, A1 polypeptide, Coagulation factor XIIIa, EC 2.3.2.13, F13Acoagulation factor XIII, A polypeptide, factor XIIIa, fibrin stabilizing factor, A subunit, fibrinoligase, FSF, A subunit, Protein-glutamine gamma-glutamyltransferase A chain, TGase, Transglutaminase A chain, transglutaminase. plasma
• Host Species: Mouse
• Molecular Weight of Antigen: 83 kDa
• Quantity: 20 μg
• Research Discipline: Apoptosis, Cancer, Cell Biology
• Gene ID (Entrez): 2162
• Target Species: Human
• Form: Purified

• Applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: F13A1/1448
• Conjugate: Unconjugated
• Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: F13A1
• Immunogen: Recombinant fragment of human Factor XIIIa protein (aa46-181) (exact sequence is proprietary)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. It recognizes a protein of 83kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans ( -/+) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG2b κ

For Research Use Only