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Invitrogen™ FADD Polyclonal Antibody
Rabbit Polyclonal Antibody
$237.00 - $511.50
Specifications
Antigen | FADD |
---|---|
Concentration | 0.55 mg/mL |
Content And Storage | -20°C |
Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
Classification | Polyclonal |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
PIPA5119104
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Invitrogen™
PA5119104 |
200 μL |
Each for $511.50
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PIPA5122008
|
Invitrogen™
PA5122008 |
20 μL |
Each for $237.00
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Description
FADD Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)
The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.Specifications
FADD | |
-20°C | |
Polyclonal | |
Liquid | |
IgG | |
Mouse | |
FADD | |
Fadd; Fas (TNFRSF6)-associated via death domain; Fas associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; Fas-associating protein with death domain; GIG3; Growth-inhibiting gene 3 protein; mediator of receptor induced toxicity; mediator of receptor-induced toxicity; MGC8528; MORT1; Mort1/FADD; protein FADD | |
FADD | |
Primary | |
Antigen Affinity Chromatography |
0.55 mg/mL | |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
Unconjugated | |
Rabbit | |
RUO | |
PBS with 50% glycerol and 0.05% ProClin 300 | |
Q61160 | |
14082 | |
Recombinant protein Fas Associating Death Domain Containing Protein. The antigen corresponds to amino acid range 7-178 of the target protein. | |
Antibody |
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