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Invitrogen™ FADD Polyclonal Antibody

Rabbit Polyclonal Antibody

$237.00 - $511.50

Specifications

Antigen FADD
Concentration 0.55 mg/mL
Content And Storage -20°C
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIPA5119104
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Invitrogen™
PA5119104
200 μL
Each for $511.50
Only null left
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PIPA5122008
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Invitrogen™
PA5122008
20 μL
Each for $237.00
Only null left
Add to Cart
 
Description

Description

FADD Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Specifications

Specifications

FADD
-20°C
Polyclonal
Liquid
IgG
Mouse
FADD
Fadd; Fas (TNFRSF6)-associated via death domain; Fas associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; Fas-associating protein with death domain; GIG3; Growth-inhibiting gene 3 protein; mediator of receptor induced toxicity; mediator of receptor-induced toxicity; MGC8528; MORT1; Mort1/FADD; protein FADD
FADD
Primary
Antigen Affinity Chromatography
0.55 mg/mL
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Unconjugated
Rabbit
RUO
PBS with 50% glycerol and 0.05% ProClin 300
Q61160
14082
Recombinant protein Fas Associating Death Domain Containing Protein. The antigen corresponds to amino acid range 7-178 of the target protein.
Antibody
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