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  7. Fasudil hydrochloride, Tocris Bioscience™

Fasudil hydrochloride, Tocris Bioscience™

Catalog Number 054110
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
105628-07-7
C14H18ClN3O2S
327.827
LFVPBERIVUNMGV-UHFFFAOYSA-N
fasudil hydrochloride, fasudil hcl, eril, at 877 hydrochloride, fasudil monohydrochloride, ha 1077 hydrochloride, unii-sq04n8s7br, 5-1,4-diazepan-1-yl sulfonyl isoquinoline hydrochloride, sq04n8s7br
163751
5-(1,4-diazepan-1-ylsulfonyl)isoquinoline;hydrochloride
C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl
This item is not returnable. View return policy
105628-07-7
C14H18ClN3O2S
327.827
LFVPBERIVUNMGV-UHFFFAOYSA-N
fasudil hydrochloride, fasudil hcl, eril, at 877 hydrochloride, fasudil monohydrochloride, ha 1077 hydrochloride, unii-sq04n8s7br, 5-1,4-diazepan-1-yl sulfonyl isoquinoline hydrochloride, sq04n8s7br
163751
5-(1,4-diazepan-1-ylsulfonyl)isoquinoline;hydrochloride
C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl

Description

Inhibitor of cyclic nucleotide dependent- and Rho-kinases

Fasudil hydrochloride is a cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM). Fasudil suppresses MMP-2 expression and induces apoptosis in glioblastoma cells in vivo. Fasudil is a Ca2+ antagonist, vasodilator and inhibits proliferation of vascular smooth muscle cells. Fasudil binds to α-synuclein to reduce aggregate formation in cellular models of Parkinson's disease, also displays neuroprotective properties and increases survival of dopaminergic neurons in vivo.
Quantity 10 mg
Formula Weight 327.83
Percent Purity >98%
Chemical Name or Material Fasudil hydrochloride

Safety and Handling

Recommended Storage Store at Room Temperature
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