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  6. Fc gamma RIIIA/CD16a Mouse anti-Human, Clone: HuNK2, Novus Biologicals™

Fc gamma RIIIA/CD16a Mouse anti-Human, Clone: HuNK2, Novus Biologicals™
SDP

Catalog No. NBP247953B Shop All R&D Systems Products
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0.2 mg
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NBP247953B 0.2 mg
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Catalog No. NBP247953B Supplier Novus Biologicals Supplier No. NBP2479530.2MG

Description

Mouse Monoclonal Antibody

Fc gamma RIIIA/CD16a Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

Antigen Fc gamma RIIIA/CD16a
Applications Flow Cytometry, Immunofluorescence, CyTOF
Classification Monoclonal
Clone HuNK2
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Formulation PBS with No Preservative
Gene Alias CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA
Gene Symbols FCGR3A
Host Species Mouse
Immunogen Human peripheral blood lymphocytes from a NK-leukemia patient.
Purification Method Protein A or G purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 2214
Test Specificity Recognizes a protein of 50-65kDa, identified as CD16 (Workshop IV; Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This MAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG2a κ
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