FDFT1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 131281AP150UL

Catalog No. 50-172-8510

Description

Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF regulates the transient response of several muscle genes in response to growth factors and recruits accessory myogenic factors to activate these muscle genes. SRF is required for the formation of vertebrate mesoderm leading to the origin of the cardiovascular system. Myocardin, in association with SRF in cardiac muscle cells, activates cardiac muscle promoters. Myocardin-related transcription factors A and B (MRTF-A and MRTF-B) interact with SRF and act as stimulators for its transcriptional activity. MRTF-B is crucial for skeletal myogenic differentiation.

Specifications

• Antigen: FDFT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FDFT1
• Gene Alias: DGPT, ERG9, FDFT1, FPP:FPP farnesyltransferase, SQS, Squalene synthase, SS
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14137, 2222, 29580
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P37268, P53798, Q02769
• Gene Symbols: FDFT1
• Immunogen: FDFT1 Fusion Protein Ag3743
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG