Tocris™ Ferrostatin 1

Selective inhibitor of erastin induced ferroptosis

Manufacturer: Tocris™ 5180/10

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Catalog No. 51-801-0

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For Research Use Only


    Product Type Ferrostatin 1
    Inhibitors Ferrostatin 1
    Purity >98
    Molecular Weight 262.35
    Quantity 10mg

    Selective inhibitor of erastin induced ferroptosis (EC50 = 60nM). Specifically inhibits Ras selective lethal compound -induced death, but not cell death induced by other oxidative lethal compounds and apoptosis-inducing agents. Inhibits ferroptosis in cancer cells; also inhibits glutamate-induced cell death in organotypic rat brain slices. Prevents erastin induced accumulation of cytosolic and lipid reactive oxygen species.

    • Chemical Name: Ethyl 3-amino-4-(cyclohexylamino)benzoate
    • Formula: C15H22N2O2
    • CAS Number: 347174-05-4
    • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
    • Purity: >98

  • Description & Specifications

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