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Fibronectin/Anastellin Mouse, Clone: TV-1, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2328490.1MG

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Catalog No. NBP232849A


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Description

Description

Fibronectin/Anastellin Monoclonal antibody specifically detects Antigen in Human, Mouse, Porcine, Rat samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blotting.
Specifications

Specifications

Fibronectin
TV-1
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml
P02751
CIGDKFZp686O13149, Cold-insoluble globulin, DKFZp686F10164, DKFZp686H0342, DKFZp686I1370, fibronectin, fibronectin 1, FNFINC, FNZ, GFND2ED-B, LETSGFND, migration-stimulating factor, MSF
Mouse
IgG1 Kappa
0.1 mg
Cancer, Cellular Markers, Extracellular Matrix, Mesenchymal Stem Cell Markers, Neuronal Stem Cell Markers, Stem Cell Markers
Primary
2335
Human, Mouse, Rat, Porcine
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Unconjugated
PBS with 0.05% BSA. with 0.05% Sodium Azide
Purified
FN1
T-cell lymphoma biopsy
Protein A purified
RUO
Store at 4C.
Monoclonal
Fibronectin is a soluble dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.
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