Fibronectin Antibody (TV-1), Alexa Fluor™ 350, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234504AF350

Catalog No. NP23404A30

Description

Fibronectin Monoclonal specifically detects Fibronectin in Human, Mouse, Rat, Porcine samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Fibronectin
• Classification: Monoclonal
• Conjugate: Alexa Fluor 350
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: FN1
• Immunogen: T-cell lymphoma biopsy
• Quantity: 0.1 mL
• Gene ID (Entrez): 2335
• Target Species: Human, Mouse, Rat, Pig
• Isotype: IgG1 κ

• Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: TV-1
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Alias: CIG, ED-B, fibronectin 1, FINC, FN, FN1, FNZ, GFND, GFND2, LETS, MSF, SMDCF
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Primary or Secondary: Primary
• Test Specificity: Fibronectin is a soluble dimeric glycoprotein of 440kDa, which is present in cells, extracellular matrix, and blood. This monoclonal antibody reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this monoclonal antibody localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating monoclonal antibody indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or monoclonal antibodys.
• Content And Storage: Store at 4°C in the dark.