Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Filaggrin Antibody (FLG/1563), DyLight 488, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP275774G
Description
Filaggrin Monoclonal specifically detects Filaggrin in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.Specifications
Filaggrin | |
Monoclonal | |
DyLight 488 | |
50mM Sodium Borate with 0.05% Sodium Azide | |
FLG | |
Recombinant human Filaggrin protein fragment (around aa 998-1104) (exact sequence is proprietary) (Uniprot: P20930) | |
0.1 mL | |
Cell Biology, Cellular Markers | |
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery. | |
Store at 4°C in the dark. |
Immunohistochemistry, Immunohistochemistry (Paraffin) | |
FLG/1563 | |
Immunohistochemistry, Immunohistochemistry-Paraffin | |
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin | |
Mouse | |
Protein A or G purified | |
RUO | |
Primary | |
Human | |
IgG2b κ |
Provide Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?
Provide Content Correction