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FIV gp95 Antibody (SU1-30), Alexa Fluor™ 488, Novus Biologicals™
SDP

Catalog No. NB10064378X Shop All R&D Systems Products
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0.125 mL
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NB10064378X 0.125 mL
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Catalog No. NB10064378X Supplier Novus Biologicals Supplier No. NB10064378AF488

Item Discontinued This item has been discontinued by the supplier. Please to view product availability in your area.

Description

Mouse Monoclonal Antibody

FIV gp95 Monoclonal specifically detects FIV gp95 in Virus samples. It is validated for Western Blot, Flow Cytometry.

Specifications

Antigen FIV gp95
Applications Western Blot, Flow Cytometry
Classification Monoclonal
Clone SU1-30
Conjugate Alexa Fluor 488
Dilution Western Blot, Flow Cytometry
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Host Species Mouse
Immunogen Made to FIV gp95
Purification Method Protein A purified
Quantity 0.125 mL
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity NB100-64378 specifically recognizes the relatively conserved E60 peptide (amino acid sequence SSWKQRNRWEWRPDF) located within the V3 region of FIV (Feline Immunodeficiency Virus) envelope glycoprotein SU,gp95. The primary receptor for FIV infection of cats has been identified as the T-cell activation antigen CD134 which, along with CXC chemokine receptor 4 (CXCR4), facilitates the infection of CD4+ primary target cells, resulting in a depletion in the CD4+ population. Studies have shown that the V3 loop of SU,gp95 is a major immunogenic domain, suggested to contain the main determinants for the binding of FIV SU,gp95 to CXCR4.(3) Clone SU1-30 has been shown to inhibit the sCD134-activated entry of both clade B and clade C FIV strains.(1) NB100-64378 does not recognize Feline Leukaemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus. Removal of Sodium Azide is recommended prior to use in functional studies.
Reconstitution Protein A purified
Target Species Virus
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1
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