FIV gp95 Antibody (SU1-30), DyLight 680, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NB10064378FR

Catalog No. NB10064378R

Description

FIV gp95 Monoclonal specifically detects FIV gp95 in Virus samples. It is validated for Western Blot, Flow Cytometry.

Specifications

• Antigen: FIV gp95
• Classification: Monoclonal
• Conjugate: DyLight 680
• Host Species: Mouse
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Test Specificity: NB100-64378 specifically recognizes the relatively conserved E60 peptide (amino acid sequence SSWKQRNRWEWRPDF) located within the V3 region of FIV (Feline Immunodeficiency Virus) envelope glycoprotein SU,gp95. The primary receptor for FIV infection of cats has been identified as the T-cell activation antigen CD134 which, along with CXC chemokine receptor 4 (CXCR4), facilitates the infection of CD4+ primary target cells, resulting in a depletion in the CD4+ population. Studies have shown that the V3 loop of SU,gp95 is a major immunogenic domain, suggested to contain the main determinants for the binding of FIV SU,gp95 to CXCR4.(3) Clone SU1-30 has been shown to inhibit the sCD134-activated entry of both clade B and clade C FIV strains.(1) NB100-64378 does not recognize Feline Leukaemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus. Removal of Sodium Azide is recommended prior to use in functional studies.
• Content And Storage: Store at 4C in the dark.
• Isotype: IgG1

• Applications: Western Blot, Flow Cytometry
• Clone: SU1-30
• Dilution: Western Blot, Flow Cytometry
• Immunogen: Made to FIV gp95
• Quantity: 0.125 mL
• Primary or Secondary: Primary
• Target Species: Virus
• Form: Purified

For Research Use Only