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Tocris Bioscience™ FK 888

Catalog No. 240010
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10 mg
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Catalog No. Quantity
24-001-0 10 mg
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Catalog No. 24-001-0 Supplier Tocris Bioscience™ Supplier No. 2400/10
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High affinity NK1 antagonist

Selective, high affinity tachykinin NK1 receptor antagonist (Ki = 0.69 nM) that displays 320-fold selectivity for human over rat NK1 receptors. Inhibits substance P-induced contraction of isolated guinea pig trachea (IC50 = 32 nM) and inhibits substance P-induced airway constriction in vivo following i.v. and oral administration.

Chemical Identifiers

CAS 138449-07-7
Molecular Formula C36H36N4O4

Specifications

Quantity 10 mg
Formula Weight 588.69
Purity >98%
Molecular Weight (g/mol) 588.708
Chemical Name or Material FK 888
Recommended Storage Store at -20°C
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