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FLNC Rabbit, anti-Human, Unconjugated, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 284921AP150UL

Encompass

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Catalog No. 50-223-8713


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Description

Description

Filamin C (FLNC; also known as γ-FLN; ABP-L; FLN2), a muscle-specific filamin and a large actin-cross-linking protein. Human filamins are ∼280 kDa homodimers, each monomer consisting of an N-terminal actin-binding domain followed by 24 immunoglobulin (Ig)-like domains (d1 to d24), the last of which mediates dimerization. FLNC is specifically expressed in cardiomyocytes and skeletal myocytes and is involved in the maintenance of structural integrity. High filamin C associated with better prognosis of prostate cancer, leukemia and breast cancer patients. ( PMID: 25577646, PMID: 30867563, PMID: 31131323)

Specifications

Specifications

FLNC
Polyclonal
Unconjugated
150 μL
2318
Liquid
Western Blot, ELISA
300 μg/mL
Rabbit
Primary
Human
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