Invitrogen™ FNDC4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5107129

Catalog No. PIPA5107129

Description

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.

Specifications

• Antigen: FNDC4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FNDC4
• Gene Alias: 2810430J06Rik; 6330410H20Rik; AB030187; AI838506; AW487863; fibronectin type III domain containing 4; fibronectin type III domain-containing protein 4; fibronectin type III repeat containing protein 1; fibronectin type III repeat-containing protein 1; Fndc4; Fnmp1; FRCP1; UNQ6389/PRO21134
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64838
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q9H6D8
• Gene Symbols: FNDC4
• Immunogen: Synthetic peptide directed towards the middle region of human FNDC4 (aa 71-121).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov