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G-CSF Antibody (SPM468) - IHC-Prediluted, Novus Biologicals™
SDP

Catalog No. NBP248381 Shop All R&D Systems Products
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NBP248381 7 mL
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Catalog No. NBP248381 Supplier Novus Biologicals Supplier No. NBP248381
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Description

Mouse Monoclonal Antibody

G-CSF Monoclonal specifically detects G-CSF in Human, Monkey, Rhesus Macaque samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen G-CSF
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone SPM468
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin
Formulation 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias C17orf33, chromosome 17 open reading frame 33, colony stimulating factor 3 (granulocyte), CSF3OS, filgrastim, G-CSF, GCSFlenograstim, granulocyte colony-stimulating factor, Lenograstim, MGC45931, pluripoietin
Gene Symbols CSF3
Host Species Mouse
Immunogen Nuclei from pokeweed mitogen stimulated human peripheral blood lymphocytes
Molecular Weight of Antigen 19 kDa
Purification Method Protein A or G purified
Quantity 7 mL
Regulatory Status RUO
Research Discipline Cell Cycle and Replication, Cytokine Research
Primary or Secondary Primary
Gene ID (Entrez) 1440
Test Specificity This monoclonal antibody recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSFs share 73% sequence identity at the amino acid level.
Target Species Human, Monkey
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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