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GADD45GIP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$518.60

Specifications

Antigen GADD45GIP1
Concentration 0.35 mg/mL
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-0835
SDP
Encompass_Preferred
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Proteintech Group Inc
162601AP150UL
150 μL
Each of 1 for $518.60
Only null left
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Description

Description

Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase that plays an essential role in the NF-kaapa-B signaling pathway which is activated by mulitple stimuli such as inflammatory cytokines, bacterial, or viral products, DNA damages, or other cellular stresses. IKK beta acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. Mutations affecting the IKK beta gene can result in Immunodeficiency 15 (IMD15).
Specifications

Specifications

GADD45GIP1
Immunoprecipitation, Western Blot
Unconjugated
Rabbit
Human, Mouse, Rat
Q8TAE8, Q9CR59
102060, 288916, 90480
GADD45GIP1 Fusion Protein Ag9299
Primary
-20°C
GADD45GIP1
0.35 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
CKBBP2, CKII beta associating protein, CR6 interacting factor 1, CRIF1, GADD45GIP1, p53 responsive gene 6 protein, PLINP 1, Plinp1, PRG6
Gadd45gip1
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

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