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Tocris Bioscience™ GANT 61
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Catalog No. 319110
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Catalog No. Quantity
31-911-0 10 mg
31-915-0 50 mg
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Catalog No. 31-911-0 Supplier Tocris Bioscience™ Supplier No. 3191/10
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Description

GLI antagonist; inhibits Hedgehog (Hh) signaling

GLI antagonist that inhibits GLI1 and GLI2-induced transcription (IC50 ∽ 5 μM). Inhibits the hedgehog (Hh) signaling pathway downstream of SMO and SUFU causing GLI1 nuclear accumulation. Displays antiproliferative and antitumor activity in vivo. Inhibits the pluripotency factors Oct4, Sox-2, Nanog and c-Myc in pancreatic cancer stem cells.

Chemical Identifiers

CAS 500579-04-4
Molecular Formula C27H35N5

Specifications

Quantity 10 mg
Formula Weight 429.61
Purity >98%
Molecular Weight (g/mol) 429.612
Chemical Name or Material GANT 61

Safety and Handling

Recommended Storage Store at -20°C
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