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Tocris Bioscience™ GC 1
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Catalog No. 455410
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45-541-0 10 mg
45-545-0 50 mg
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Catalog No. 45-541-0 Supplier Tocris Bioscience™ Supplier No. 4554/10
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Description

High affinity thyroid receptor α (TRα) and TRβ agonist; thyromimetic

Thyromimetic; high affinity agonist at thyroid hormone receptor (TR) β and TRα receptors (KD values are 67 and 440 pM respectively). Displays 5- and 100-fold greater potency than the endogenous agonist T3 in vitro at TRα1 and TRβ1 receptors respectively. Promotes reverse cholesterol transport in chow- and fat-fed mice. Induces proliferation of hepatocytes and pancreatic acinar cells in rats independent of prior tissue injury.

Chemical Identifiers

CAS 211110-63-3
Molecular Formula C20H24O4

Specifications

Quantity 10 mg
Formula Weight 328.4
Purity >98%
Molecular Weight (g/mol) 328.408
Chemical Name or Material GC 1

Safety and Handling

Recommended Storage Store at -20°C
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