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  6. GCH1 Monoclonal Antibody (OTI8C6), TrueMAB™, OriGene 

GCH1 Monoclonal Antibody (OTI8C6), TrueMAB™, OriGene
SDP

Catalog No. p-200016420
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100 μL
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Catalog No. Quantity
50-168-3282 100 μL
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Catalog No. 50-168-3282 Supplier OriGene Supplier No. TA810249
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Description

Mouse Monoclonal Antibody

This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with maligt hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.

Specifications

Antigen GCH1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI8C6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene GCH1
Gene Accession No. P30793
Gene Alias DYT14, DYT5, DYT5a, GCH, GTP-CH-1, GTPCH1, HPABH4B
Gene Symbols GCH1
Host Species Mouse
Immunogen Full length human recombit protein of human GCH1 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2643
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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