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Invitrogen™ GCLM Recombinant Rabbit Monoclonal Antibody (0U3J2)
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Catalog No. PIMA537836
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100 μL
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PIMA537836 100 μL
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Catalog No. PIMA537836 Supplier Invitrogen™ Supplier No. MA537836
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: U2OS, HeLa, A-431 Immunogen sequence: LYQWAQVKPN SNQVNLASCC VMPPDLTAFA KQFDIQLLTH NDPKELLSEA SFQEALQESI PDIQAHEWVP LWLLRYSVIV KSRGIIKSKG YILQAKRRGS.

Gamma-glutamylcysteine synthetase (gamma-GCS) is the rate limiting enzyme for glutathione (L-gamma-glutamyl-L-cysteinylglycine, GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. Gamma-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic ntioxidants, heat shock, oxidants and cytokines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GCLM
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 0U3J2
Concentration 1.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Gclm
Gene Accession No. P48507
Gene Alias AI649393; gamma glutamylcysteine synthetase; gamma-ECS regulatory subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Gclm; Gcmc; GCS light chain; Glclr; glutamate cysteine ligase (gamma-glutamylcysteine synthetase), regulatory; glutamate cysteine ligase, modifier subunit; glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD); glutamate-cysteine ligase modifier subunit; glutamate--cysteine ligase modifier subunit; glutamate-cysteine ligase modifier subunit delta2 alternative splicing; glutamate-cysteine ligase regulatory protein; Glutamate--cysteine ligase regulatory subunit; glutamate-cysteine ligase, modifier subunit; GSC light chain; null
Gene Symbols Gclm
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 175-274 of human GCLM (P48507).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2730
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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