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Gelsolin Mouse, Unlabeled, Clone: 2, BD

Catalog No. BDB610412 Shop All BD Biosciences Products
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Catalog No. Quantity
BDB610412 50 μg
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Catalog No. BDB610412 Supplier BD Biosciences Supplier No. 610412

Description

Mouse Monoclonal Antibody

Gelsolin was identified as a result of its ability to sever actin filaments in a Ca2+-dependent manner. The gene for gelsolin encodes an 83kDa protein that migrates as a 93kDa polypeptide in SDS-gels. The N-terminal domain contains the calcium-independent actin-severin site, whereas the calcium-dependent site is located in the C-terminal portion of the protein. It exhibits significant homology with villin, another calcium-regulated actin filament severing protein. Gelsolin can be found intracellularly, as well as in a secreted form. However, both forms are encoded by the same gene.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Gelsolin
Applications Western Blot
Classification Monoclonal
Clone 2
Concentration 250μg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Canine, Human, Mouse, Rabbit, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG2a
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For Research Use Only.

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