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Gelsolin Mouse, Unlabeled, Clone: 2, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 610412
Description
Gelsolin was identified as a result of its ability to sever actin filaments in a Ca2+-dependent manner. The gene for gelsolin encodes an 83kDa protein that migrates as a 93kDa polypeptide in SDS-gels. The N-terminal domain contains the calcium-independent actin-severin site, whereas the calcium-dependent site is located in the C-terminal portion of the protein. It exhibits significant homology with villin, another calcium-regulated actin filament severing protein. Gelsolin can be found intracellularly, as well as in a secreted form. However, both forms are encoded by the same gene.
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Specifications
Gelsolin | |
Monoclonal | |
250μg/mL | |
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
50 μg | |
Cell Biology | |
Canine, Human, Mouse, Rabbit, Rat | |
IgG2a |
Western Blot | |
2 | |
Unconjugated | |
Mouse | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at -20°C. |
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For Research Use Only.