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Thermo Scientific™ GeneBLAzer™ AVPR2-CRE-bla CHO-K1 Cells
Description
GeneBLAzer™ AVPR2 CRE-bla CHO-K1 cells contain the human Arginine Vasopressin 2 (AVPR2) receptor stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat. No. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.
The GeneBLAzer™ AVPR2 CRE-bla CHO-K1 cells are functionally validated for Z' and EC50 concentrations of dDAVP. In addition, GeneBLAzer™ AVPR2 CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.
Agonists and antagonists of the AVPR2 receptors are in various stages of clinical trials for the treatment of hypertension and as diuretics.
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Specifications
Specifications
| Accession Number | NM_000054 |
| Assay Entry | Cell-based beta lactamase reporter gene |
| Cell State | Dividing Cells |
| Content And Storage | LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol. Includes: • GeneBLAzer™ AVPR2 CRE-bla CHO-K1 cells • GeneBLAzer™ AVPR2 CRE-bla CHO-K1 Assay Protocol • Certificate of Analysis The GeneBLAzer™ AVPR2 CRE-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt. |
| Detection Method | Fluorescence |
| For Use With (Application) | FRET |
| Gene Symbol | AVPR2 |
| Population Status | Single Cell Clone Origin |
| Product Line | GeneBLAzer |
| Quantity | 2 x 106 Cells |
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For Research Use Only. Not for use in diagnostic procedures.
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